Martha Cyert

Publications

• Curcumin inhibits growth of Saccharomyces cerevisiae through iron chelation. Minear S, O'Donnell AF, Ballew A, Giaever G, Nislow C, Stearns T, Cyert MS. Eukaryot Cell. 2011; 10 (11): 1574-81
• Hph1 and Hph2 are novel components of the Sec63/Sec62 posttranslational translocation complex that aid in vacuolar proton ATPase biogenesis. Piña FJ, O'Donnell AF, Pagant S, Piao HL, Miller JP, Fields S, Miller EA, Cyert MS. Eukaryot Cell. 2011; 10 (1): 63-71
• Alpha-arrestins Aly1 and Aly2 regulate intracellular trafficking in response to nutrient signaling. O'Donnell AF, Apffel A, Gardner RG, Cyert MS. Mol Biol Cell. 2010; 21 (20): 3552-66
• A conserved docking surface on calcineurin mediates interaction with substrates and immunosuppressants. Rodríguez A, Roy J, Martínez-Martínez S, López-Maderuelo MD, Niño-Moreno P, Ortí L, Pantoja-Uceda D, Pineda-Lucena A, Cyert MS, Redondo JM. Mol Cell. 2009; 33 (5): 616-26
• Cracking the phosphatase code: docking interactions determine substrate specificity. Roy J, Cyert MS. Sci Signal. 2009; 2 (100): re9
• A conserved docking site modulates substrate affinity for calcineurin, signaling output, and in vivo function. Roy J, Li H, Hogan PG, Cyert MS. Mol Cell. 2007; 25 (6): 889-901
• Renaming the DSCR1/Adapt78 gene family as RCAN: regulators of calcineurin. Davies KJ, Ermak G, Rothermel BA, Pritchard M, Heitman J, Ahnn J, Henrique-Silva F, Crawford D, Canaider S, Strippoli P, Carinci P, Min KT, Fox DS, Cunningham KW, Bassel-Duby R, Olson EN, Zhang Z, Williams RS, Gerber HP, Pérez-Riba M, Seo H, Cao X, Klee CB, Redondo JM, Maltais LJ, Bruford EA, Povey S, Molkentin JD, McKeon FD, Duh EJ, Crabtree GR, Cyert MS, de la Luna S, Estivill X. FASEB J. 2007; 21 (12): 3023-8
• Slm1 and slm2 are novel substrates of the calcineurin phosphatase required for heat stress-induced endocytosis of the yeast uracil permease. Bultynck G, Heath VL, Majeed AP, Galan JM, Haguenauer-Tsapis R, Cyert MS. Mol Cell Biol. 2006; 26 (12): 4729-45
• Genomic and proteomic comparisons between bacterial and archaeal genomes and related comparisons with the yeast and fly genomes. Karlin S, Brocchieri L, Campbell A, Cyert M, Mrázek J. Proc Natl Acad Sci U S A. 2005; 102 (20): 7309-14
• Molecular analysis reveals localization of Saccharomyces cerevisiae protein kinase C to sites of polarized growth and Pkc1p targeting to the nucleus and mitotic spindle. Denis V, Cyert MS. Eukaryot Cell. 2005; 4 (1): 36-45
• Hph1p and Hph2p, novel components of calcineurin-mediated stress responses in Saccharomyces cerevisiae. Heath VL, Shaw SL, Roy S, Cyert MS. Eukaryot Cell. 2004; 3 (3): 695-704
• Integration of stress responses: modulation of calcineurin signaling in Saccharomyces cerevisiae by protein kinase A. Kafadar KA, Cyert MS. Eukaryot Cell. 2004; 3 (5): 1147-53
• Calcineurin signaling in Saccharomyces cerevisiae: how yeast go crazy in response to stress. Cyert MS, Biochem Biophys Res Commun. 2003; 311 (4): 1143-50
• Negative regulation of calcineurin signaling by Hrr25p, a yeast homolog of casein kinase I. Kafadar KA, Zhu H, Snyder M, Cyert MS. Genes Dev. 2003; 17 (21): 2698-708
• Calcineurin-dependent regulation of Crz1p nuclear export requires Msn5p and a conserved calcineurin docking site. Boustany LM, Cyert MS. Genes Dev. 2002; 16 (5): 608-19
• Genome-wide analysis of gene expression regulated by the calcineurin/Crz1p signaling pathway in Saccharomyces cerevisiae. Yoshimoto H, Saltsman K, Gasch AP, Li HX, Ogawa N, Botstein D, Brown PO, Cyert MS. J Biol Chem. 2002; 277 (34): 31079-88
• Internal Ca(2+) release in yeast is triggered by hypertonic shock and mediated by a TRP channel homologue. Denis V, Cyert MS. J Cell Biol. 2002; 156 (1): 29-34
• Calcineurin-dependent nuclear import of the transcription factor Crz1p requires Nmd5p. Polizotto RS, Cyert MS. J Cell Biol. 2001; 154 (5): 951-60
• Genetic analysis of calmodulin and its targets in Saccharomyces cerevisiae. Cyert MS, Annu Rev Genet. 2001: 35 647-72
• Regulation of nuclear localization during signaling. Cyert MS, J Biol Chem. 2001; 276 (24): 20805-8
• The eukaryotic response regulator Skn7p regulates calcineurin signaling through stabilization of Crz1p. Williams KE, Cyert MS. EMBO J. 2001; 20 (13): 3473-83
• Luv1p/Rki1p/Tcs3p/Vps54p, a yeast protein that localizes to the late Golgi and early endosome, is required for normal vacuolar morphology. Conboy MJ, Cyert MS. Mol Biol Cell. 2000; 11 (7): 2429-43
• Identification of a novel region critical for calcineurin function in vivo and in vitro. Jiang B, Cyert MS. J Biol Chem. 1999; 274 (26): 18543-51
• Yeast calcineurin regulates nuclear localization of the Crz1p transcription factor through dephosphorylation. Stathopoulos-Gerontides A, Guo JJ, Cyert MS. Genes Dev. 1999; 13 (7): 798-803
• Ion tolerance of Saccharomyces cerevisiae lacking the Ca2+/CaM-dependent phosphatase (calcineurin) is improved by mutations in URE2 or PMA1. Withee JL, Sen R, Cyert MS. Genetics. 1998; 149 (2): 865-78
• An essential role of the yeast pheromone-induced Ca2+ signal is to activate calcineurin. Withee JL, Mulholland J, Jeng R, Cyert MS. Mol Biol Cell. 1997; 8 (2): 263-77
• Calcineurin acts through the CRZ1/TCN1-encoded transcription factor to regulate gene expression in yeast. Stathopoulos AM, Cyert MS. Genes Dev. 1997; 11 (24): 3432-44
• The product of HUM1, a novel yeast gene, is required for vacuolar Ca2+/H+ exchange and is related to mammalian Na+/Ca2+ exchangers. Pozos TC, Sekler I, Cyert MS. Mol Cell Biol. 1996; 16 (7): 3730-41
• Calcineurin, the Ca2+/calmodulin-dependent protein phosphatase, is essential in yeast mutants with cell integrity defects and in mutants that lack a functional vacuolar H(+)-ATPase. Garrett-Engele P, Moilanen B, Cyert MS. Mol Cell Biol. 1995; 15 (8): 4103-14